منابع مشابه
Familial Acute Myelogenous Leukemia: Report of Three Cases
Acute myelogenous leukemia (AML) is a hematological malignancy, which accounts for about 15-25% of childhood's leukemia. Genetic factor is one of the most important predisposing elements in childhood acute leukemia, especially AML. In this case report, a rare presentation of familial AML is presented in three monozygotic triplets. Two were 10 months old, and the other one was 16 months old at p...
متن کاملFlow Cytometry in Chronic Myelogenous Leukemia Blast Crisis
Background: Chronic myelogenous leukemia (CML) is a myeloproliferative disorder due to BCR-ABL1 translocation. Patients showing transformation into blast crisis (BC) have poorer treatment response and prognosis. Methods: A retrospective study was conducted in the department of Pathology, Maulana Azad Medical College, New Delhi, India, over a time period of 5 years (2014-2019) to evaluate the ...
متن کاملDemonstration of a chronic myelogenous leukemia clone in acute myelogenous leukemia
In the present study, we report a case of a 58-year-old female patient presenting with Philadelphiachromosome (Ph)-negative blast cells and Ph -positive mature cells at diagnosis. The complete blood cell count showed the patient had a white blood cell count of 35.5 × 109/L and a differential blast count of 62%. A bone marrow biopsy showed closely packed marrow with blast cell infiltration. Blas...
متن کاملChronic myelogenous leukemia.
The treatment recommendations for chronic myelogenous leukemia (CML) are evolving rapidly. In the past year, pegylated interferon and STI571 (Gleevec, imatinib mesylate), a Bcr-Abl tyrosine kinase inhibitor, have become commercially available and non-myeloablative stem cell transplants continue to be refined. Clinicians and patients face a bewildering array of treatment options for CML. In this...
متن کاملChronic myelogenous leukemia.
Received for publication 29 September 1980 and in revised form 12 January 198
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ژورنال
عنوان ژورنال: Cancer Cell
سال: 2004
ISSN: 1535-6108
DOI: 10.1016/j.ccr.2004.12.005